Alone among herpesviruses, persistent Cytomegalovirus (CMV) markedly alters the numbers
and proportions of peripheral immune cells in infected-vs-uninfected people. Because the …

Cytolytic CD8 T cells play a crucial role in the control and elimination of virus-infected cells
and are a major focus of HIV cure efforts. However, it has been shown that HIV-specific CD8 T …

Altered interactions between the gut mucosa and bacteria during HIV infection seem to
contribute to chronic immune dysfunction. A deeper understanding of how nutritional …

Immunosenescence is characterized by phenotypic and functional changes of effector
memory T cells. In spite of the well-described senescent defects of these experienced T cells, …

Immunosenescence, defined as the age-associated dysregulation and dysfunction of the
immune system, is characterized by impaired protective immunity and decreased efficacy of …

Relationship between thymic function and elderly survival has been suspected, despite the
fact that formal proof is elusive due to technical limitations of thymic function-related markers. …

Methods: Little is known about the immune status of preterm neonates; therefore, we analyzed
the frequency and absolute counts of different immune populations in 211 cord blood …

Levels of soluble CD14 (sCD14) were longitudinally measured in 85 human immunodeficiency
virus (HIV)–infected subjects during long-term receipt of suppressive combined …

Objectives To analyse the role of thymic function and its association with cellular immunosenescence
markers in patients with low-level CD4 T cell repopulation, despite complete HIV …

Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies.
CD8 + T cells play a critical role in control of HIV, but their functional attributes in lymph nodes …