Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation
of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis …

The spatiotemporal organization and dynamics of chromatin play critical roles in regulating
genome function. However, visualizing specific, endogenous genomic loci remains …

Guanylyl cyclases are a family of enzymes that catalyze the conversion of GTP to cGMP. The
family comprises both membrane-bound and soluble isoforms that are expressed in nearly …

T cells can be re-directed to kill cancer cells using chimeric antigen receptors (CARs) or T
cell receptors (TCRs). This approach, however, is constrained by the rarity of tumor-specific …

Label-free nanosensors can detect disease markers to provide point-of-care diagnosis that is
low-cost, rapid, specific and sensitive 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 . However, …

The tumour microenvironment thwarts conventional immunotherapy through multiple immunologic
mechanisms, such as the secretion of the transforming growth factor-β (TGF-β), which …

The present paper proposes a customer–brand relationships model and empirically tests
the following: (1) brand–self distance and brand prominence as representing customers' …

Background The debriefing process during simulation-based education has been poorly
studied despite its educational importance. Videotape feedback is an adjunct that may enhance …

This research demonstrates that the positive effects of brand logos on customer brand
commitment and firm performance derive not from enabling brand identification, as is currently …

The encapsulation of cytotoxic chemotherapeutic agents in biodegradable poly (lactic-co-glycolic
acid)(PLGA) nanoparticles may offer advantages over other delivery systems, …