Achieving cost-neutrality with long-acting reversible contraceptive methods

Contraception. 2015 Jan;91(1):49-56. doi: 10.1016/j.contraception.2014.08.011. Epub 2014 Sep 6.

Abstract

Objectives: This analysis aimed to estimate the average annual cost of available reversible contraceptive methods in the United States. In line with literature suggesting long-acting reversible contraceptive (LARC) methods become increasingly cost-saving with extended duration of use, it aimed to also quantify minimum duration of use required for LARC methods to achieve cost-neutrality relative to other reversible contraceptive methods while taking into consideration discontinuation.

Study design: A three-state economic model was developed to estimate relative costs of no method (chance), four short-acting reversible (SARC) methods (oral contraceptive, ring, patch and injection) and three LARC methods [implant, copper intrauterine device (IUD) and levonorgestrel intrauterine system (LNG-IUS) 20 mcg/24 h (total content 52 mg)]. The analysis was conducted over a 5-year time horizon in 1000 women aged 20-29 years. Method-specific failure and discontinuation rates were based on published literature. Costs associated with drug acquisition, administration and failure (defined as an unintended pregnancy) were considered. Key model outputs were annual average cost per method and minimum duration of LARC method usage to achieve cost-savings compared to SARC methods.

Results: The two least expensive methods were copper IUD ($304 per women, per year) and LNG-IUS 20 mcg/24 h ($308). Cost of SARC methods ranged between $432 (injection) and $730 (patch), per women, per year. A minimum of 2.1 years of LARC usage would result in cost-savings compared to SARC usage.

Conclusions: This analysis finds that even if LARC methods are not used for their full durations of efficacy, they become cost-saving relative to SARC methods within 3 years of use.

Implications: Previous economic arguments in support of using LARC methods have been criticized for not considering that LARC methods are not always used for their full duration of efficacy. This study calculated that cost-savings from LARC methods relative to SARC methods, with discontinuation rates considered, can be realized within 3 years.

Keywords: Cost savings; Cost study; LARC; SARC; Unintended pregnancy.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cohort Studies
  • Contraception / adverse effects
  • Contraception / economics*
  • Contraceptive Agents, Female / administration & dosage
  • Contraceptive Agents, Female / adverse effects
  • Contraceptive Agents, Female / economics
  • Contraceptive Devices, Female / adverse effects
  • Contraceptive Devices, Female / economics
  • Cost Savings*
  • Costs and Cost Analysis
  • Delayed-Action Preparations / administration & dosage
  • Delayed-Action Preparations / adverse effects
  • Delayed-Action Preparations / economics
  • Drug Costs
  • Female
  • Health Care Costs
  • Humans
  • Models, Economic*
  • Pregnancy
  • Pregnancy, Unplanned
  • Time Factors
  • Transdermal Patch / adverse effects
  • Transdermal Patch / economics
  • United States
  • Young Adult

Substances

  • Contraceptive Agents, Female
  • Delayed-Action Preparations