Elsevier

Public Health

Volume 114, Issue 5, September 2000, Pages 308-315
Public Health

Articles
Physical activity and cause-specific mortality in the Whitehall study

https://doi.org/10.1038/sj.ph.1900675Get rights and content

Abstract

A prospective cohort study of London civil servants was used to examine the relation of physical activity to various causes of death.

6,702 men aged 40–64 y who participated in a baseline examination between 1969 and 1970 were followed up for 25 y during which time there were 2859 deaths. The association of two measures of physical activity (leisure time activity and usual walking pace) with cause-specific mortality was examined. Walking pace demonstrated inverse relations with mortality from all-causes, coronary heart disease (CHD), other cardiovascular disease (CVD), all cancers, respiratory disease, colorectal cancer and haematopoietic cancer following adjustment for risk factors which included age, employment grade, smoking, body mass index, and forced expiratory volume (P [trend]<0.05 for all). In analyses restricted to men without disease at entry, walking pace retained inverse associations with all-cause, CHD, other cardiovascular disease, and haematopoietic cancer mortality (P [trend]<0.05 for all). Leisure time activity was also inversely associated with mortality from all-causes, CHD, other CVD, and all-cancers following adjustment for risk factors (P [trend]<0.05 for all). Eliminating deaths in the first 5 and 10 y of follow-up did not greatly alter these associations. It is concluded that physical activity may confer protection against death due to some cancers, in addition to reducing cardiovascular disease risk. Public Health(2000) 114, 308–315

References (52)

  • JA Berlin et al.

    A meta-analysis of physical activity in the prevention of coronary heart disease

    Am J Epidemiol

    (1990)
  • CB Eaton

    Relation of physical activity and cardiovascular fitness to coronary heart disease, part I: a meta-analysis of the independent relation of physical activity and coronary heart disease

    J Am Board Fam Pract.

    (1992)
  • SN Blair

    Physical activity, fitness and coronary heart disease

  • The effects of physical activity on health and disease

    Physical activity and health: a report of the surgeon general

    (1996)
  • SA Oliveria et al.

    Is exercise beneficial in the prevention of prostate cancer?

    Sports Med.

    (1997)
  • I-M Lee

    Physical activity, fitness, and cancer

  • RJ Shephard

    Exercise and cancer: linkages with obesity?

    Crit Rev Food Sci Nutr

    (1996)
  • GA Rose

    The diagnosis of ischaemic heart pain and intermittent claudication in field studies

    Bull WHO

    (1962)
  • Definition and classification of chronic bronchitis

    Lancet.

    (1965)
  • G Rose

    The coding of survey electrocardiograms by technicians

    Br Heart J.

    (1965)
  • GA Rose et al.

    Cardiovascular Survey Methods. (WHO Monograph Series No. 56)

    (1968)
  • RJ Jarrett et al.

    Physical activity, glucose tolerance, and diabetes mellitus: the Whitehall study

    Diabetic Med.

    (1986)
  • DR Cox

    Regression models and life-tables

    JR Stat Soc (B)

    (1972)
  • M Marmot

    Changing habits of the community to prevent coronary heart disease

  • I-M Lee et al.

    Time trends in physical activity among college alumni 1962-1988

    Am J Epidemiol

    (1992)
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